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June 7, 2021 - Your Heart, Mitochondria, Energy Levels and Fat Reduction

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Your Heart, Mitochondria, Energy Levels and Fat Reduction

June 7, 2021 Puzzle Piece

Carnitine has been studied extensively because it is important to energy production and is a well-tolerated and generally safe therapeutic agent. Researchers prefer acetyl-L-carnitine because it is better absorbed in the small intestine than other forms, and more efficiently crosses the blood-brain barrier.
 
Carnitine is found in almost every cell in the body and plays a critical role in energy production by transporting fatty acids to mitochondria, where they are converted to energy. Carnitine also plays a role in helping remove toxins from cells.
 
You mainly find dietary carnitine in meat, fish, poultry and dairy, especially red meat. For vegetarians and those who avoid red meat, along with those genetically predisposed to not using certain fats for energy, it can be easy to become deficient in carnitine. There are also pre-existing health conditions that can create dysfunction:
 
  • Liver disease
  • Kidney disease, especially with dialysis
  • Digestive disease that causes poor absorption
  • Malnutrition
  • Mitochondrial disease
  • Certain metabolic disorders
  • Certain medicines, such as valproate
 
Ultimately, a deficiency leads to a condition where nutrients cannot reach your body’s cells, causing weakness and potentially heart and liver problems. Consider Essential L-Carnitine, formulated by Marc Harris, MD, ND, PhD 3.

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Signs of a Carnitine Deficiency
  • Decreased, poor muscle tone or muscle weakness
  • Tiredness (fatigue)
  • Irritability
  • Inability to lose body fat
 
L-Carnitine and Your Heart
Cardiovascular disease is a leading cause of deaths worldwide, accounting for 15-17% of healthcare costs. Current records estimate an annual global average of 30 million cardiac dysfunction cases, and experts anticipate that number to rise over the next 3 decades.
 
Studies show that L-carnitine improves the transport of long-chain fatty acids into the mitochondrial matrix, triggering cardioprotective effects through reduced oxidative stress, inflammation, and cell death. Carnitine deficiency results in a reduced oxidation (breakdown) of fatty acids and therefore, reduced energy (ATP) production.  Also consider Opti-Heart for further heart support.

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“Carnitines have an essential role in the regulation of mitochondrial function and recent studies both in animal models and human subjects have emphasized the importance of mitochondrial function in regulating NO* signaling,” said researchers from the 2009 study on “Carnitine homeostasis, mitochondrial function, and cardiovascular disease.” *NO stands for nitric oxide, a key molecule for blood vessel flexibility and blood flow.  Consider for further nutritional support Optimal Opti-BFF.

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A weakened heart will not be able to pump blood as well. This can lead to symptoms such as swelling and shortness of breath. Untreated heart weakness may lead to death early in life.
 
Several studies have examined the effectiveness of supplemental carnitine in the management of cardiac ischemia (restriction of blood flow to the heart) and peripheral arterial disease (whose most important symptom is poor circulation in the legs, known as intermittent claudication). Because levels of carnitine are low in the failing heart muscle, supplemental amounts might counteract the toxic effects of free fatty acids and improve carbohydrate metabolism.
 
L-Carnitine and Your Mitochondria
Mitochondria are the energy factories of every cell in your body. If they slow down, you slow down.
 
A decline in mitochondrial function is thought to contribute to the aging process. Carnitine may be involved because its concentration in tissues declines with age, which deteriorates the mitochondrial membrane. Carnitines are involved in mitochondrial transport of fatty acids and are of critical importance for maintaining normal mitochondrial function.  Also consider Opti-Mito for further mitochondrial nutritional support.

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L-Carnitine and the Rest of Your Body
Research on aged rats found supplementation with high doses of acetyl-L-carnitine (ALC) and ALA (an antioxidant) reduced deterioration. The animals’ activity levels rose in the form of moving around more and improved their performance on memory challenges.
 
The results suggest that acetyl-L-carnitine may help with cognitive impairment and Alzheimer’s disease. Several studies show improvements or slower declines in mental ability in people with Alzheimer's disease who took ALC.  Also consider Opti-Brain.

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Once ALC passes through the blood-brain barrier, it helps promote synthetization of a primary neurotransmitter in the brain known as acetylcholine, which primarily allows for communication between nerve cells. This in turn helps support memory, focus and alertness, improved sleep, and muscle contractions.
 
L-carnitine has also been shown to play a role in regulating calcium influx, making sure it stays out of your arteries and in your bones. Heart weakness is a serious possible development from an L-carnitine deficiency left unchecked. Also consider Essential DAK1K2.

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Research also shows that people with prediabetes had some improvement in their blood sugar levels after taking ALC for two months.
 
Researchers from the study on “L-Carnitine and heart disease” said, “L-carnitine reduces hypertension, hyperlipidemia, diabetic ketoacidosis, hyperglycemia, insulin-dependent diabetes mellitus, insulin resistance, obesity, etc.  These conditions enhance cardiovascular pathology.”
 
The Best, Most Absorbable (and Most Studied) Form of ALC
There are two forms of carnitine supplementation out there, but studies show that acetyl-L-carnitine is the superior form due to its ability to cross the blood-brain barrier. This supports brain energy and function.
 
Dr Harris’s constant assimilation of the literature in three languages, and his over 40 years of clinical experience allows Optimal Health Systems’, to create superior formulations.  Essential L-Carnitine allows the body to boost mitochondrial function, heart health, and optimal fat burn for energy and a leaner figure.
 
Yours in Health and Wellness,
 
Marc Harris, MD, ND, PhD 3
John W Brimhall, DC, BA, BS, FIAMA, DIBAK
Doug Grant, BS, ACSM

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